Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel

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Long-term consequences of repetitive brain trauma: chronic traumatic encephalopathy.

Chronic traumatic encephalopathy (CTE) has been linked to participation in contact sports such as boxing and American football. CTE results in a progressive decline of memory and cognition, as well as depression, suicidal behavior, poor impulse control, aggressiveness, parkinsonism, and, eventually, dementia. In some individuals, it is associated with motor neuron disease, referred to as chroni...

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Almost a century ago, the first clinical account of the punch-drunk syndrome emerged, describing chronic neurological and neuropsychiatric sequelae occurring in former boxers. Thereafter, throughout the twentieth century, further reports added to our understanding of the neuropathological consequences of a career in boxing, leading to descriptions of a distinct neurodegenerative pathology, term...

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Sub-Chronic Neuropathological and Biochemical Changes in Mouse Visual System after Repetitive Mild Traumatic Brain Injury.

Repetitive mild traumatic brain injury (r-mTBI) results in neuropathological and biochemical consequences in the human visual system. Using a recently developed mouse model of r-mTBI, with control mice receiving repetitive anesthesia alone (r-sham) we assessed the effects on the retina and optic nerve using histology, immunohistochemistry, proteomic and lipidomic analyses at 3 weeks post injury...

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Concussion Supplement Long-term Consequences of Repetitive Brain Trauma: Chronic Traumatic Encephalopathy

Chronic traumatic encephalopathy (CTE) has been linked to participation in contact sports such as boxing and American football. CTE results in a progressive decline of memory and cognition, as well as depression, suicidal behavior, poor impulse control, aggressiveness, parkinsonism, and, eventually, dementia. In some individuals, it is associated with motor neuron disease, referred to as chroni...

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characteristics of post-traumatic headaches following mild traumatic brain injury in military personnel

objectives this study evaluated the prevalence and characteristics of posttraumatic headaches attributed to mild brain injury in military personnel in isfahan. materials and methods a prospective, observational, descriptive study was conducted with a cohort of military personnel in military training during a 6-month period at the military training center in isfahan, iran. a total of 322 militar...

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ژورنال

عنوان ژورنال: Alzheimer's Research & Therapy

سال: 2014

ISSN: 1758-9193

DOI: 10.1186/alzrt234